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For the duration of meiotic prophase I, after telomere attachment towards the INM, phosphorylation of TERB1 triggers a phenomenon often known as telomere cap exchange [37]. During this process, the shelterin intricate appears for being temporarily displaced from the telomeric DNA, and changed by meiotic proteins TERB1, TERB2, and MAJIN. Cap Trade s

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promoter mutations lead to tumorigenesis inside a two-step mechanism. All those mutations in the Preliminary phase, in lieu of preventing bulk telomere shortening, increase the cellular lifespan by stabilizing the shortest telomeres.Telomeres are really conserved tandem nucleotide repeats that consist of proximal double-stranded and distal one-stra

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